Inactivation of Burkholderia mallei in Equine Serum for Laboratory Use: TABLE 1
نویسندگان
چکیده
منابع مشابه
Inactivation of Burkholderia mallei in Equine Serum for Laboratory Use.
1 2 Lorraine Perrett and Ian Mawhinney 3 Animal and Plant Health Agency (UK) 4 5 6 The bacterium Burkholderia mallei is the cause of glanders. In the UK the disease was 7 eradicated from horses and other equids in 1928 and is now rarely reported 8 throughout the world. Freedom from disease is maintained in part by serological 9 screening prior to international travel. Serological testing is usu...
متن کاملUse of the Common Marmoset to Study Burkholderia mallei Infection
Burkholderia mallei is a host-adapted bacterium that does not persist outside of its equine reservoir. The organism causes the zoonosis glanders, which is endemic in Asia, Africa, the Middle East and South America. Infection by B. mallei typically occurs via the respiratory or percutaneous route, and the most common manifestations are life-threatening pneumonia and bacteremia. Glanders is diffi...
متن کاملNatural Burkholderia mallei Infection in Dromedary, Bahrain
We confirm a natural infection of dromedaries with glanders. Multilocus variable number tandem repeat analysis of a Burkholderia mallei strain isolated from a diseased dromedary in Bahrain revealed close genetic proximity to strain Dubai 7, which caused an outbreak of glanders in horses in the United Arab Emirates in 2004.
متن کاملInactivation of [Fe-S] Metalloproteins Mediates Nitric Oxide-Dependent Killing of Burkholderia mallei
BACKGROUND Much remains to be known about the mechanisms by which O(2)-dependent host defenses mediate broad antimicrobial activity. METHODOLOGY/PRINCIPAL FINDINGS We show herein that reactive nitrogen species (RNS) generated by inducible nitric oxide (NO) synthase (iNOS) account for the anti-Burkholderia mallei activity of IFNgamma-primed macrophages. Inducible NOS-mediated intracellular kil...
متن کاملDevelopment of Burkholderia mallei and pseudomallei vaccines
Burkholderia mallei and Burkholderia pseudomallei are Gram-negative bacteria that cause glanders and melioidosis, respectively. Inhalational infection with either organism can result in severe and rapidly fatal pneumonia. Inoculation by the oral and cutaneous routes can also produce infection. Chronic infection may develop after recovery from acute infection with both agents, and control of inf...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Microbiology
سال: 2015
ISSN: 0095-1137,1098-660X
DOI: 10.1128/jcm.03141-14